Next-Gen
Immunotargeting & Immunotheragnostics.....
..... is here
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Radio-sensitization
Our proprietary technology targets and specifically sensitizes cancer cells in such a way that they show enhanced response (cell death) to radiation
Targeted payload delivery
Be it carrying a therapeutic payload or an imaging agent to monitor response or a combination of both – we are developing specific targeting moieties tethered to liposomes in formulation that enables targeted delivery to cancer cells.
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Therapeutics
Our pipeline of antibodies and single chain variable fragments (scFv’s) have demonstrated cytotoxic effects against cancer cells, specifically towards Non-Small Cell
Our Company
OUR STORY
Medical Guidance Systems, founded in 2013, aims to operate in the cancer immunotherapy and nanotechnology-enabled drug delivery market, by providing new targeted theragnostic opportunities for patients diagnosed with poor prognosis cancers.
OUR VISION
To provide theragnostic solutions to poor prognosis cancer and thereby elevate cancer care.
OUR TECHNOLOGY
We have discovered and prioritized inducible antigens in cancer. These have been prioritized based upon cancer specificity and the widest spectrum of cancer subtypes that show induction. Our lead antibodies to inducible antigens show cancer specificity and prolonged binding on the surface of cancer cells. The company is aimed at generation of theragnostic products using our multiple lead molecular targets under two broad platforms, Ligand Directed and Antibody Directed.
Our Company
Dennis Hallahan, MD.
Founder
Dennis Hallahan, MD has started 5 biotechnology companies, 2 of them publicly traded (Genvec, Inc.& Cumberland Emerging Technologies). Dr. Hallahan has established several service companies. He has experience of launching and exiting from companies that he has founded. Dr. Hallahan has developed several drugs that have entered Phase I through Phase III clinical trials.
Stephanie Hallahan, MBA.
President & CEO
Stephanie Hallahan, MBA as our President and CEO, leading the company. She has been in this position since 2013 and has had direct oversight of phase I STTR and SBIR grants and phase II SBIR grants. She had a successful combined 20 years of career managing research teams, IP, and licensing. This career included management of millions in budgets and negotiations of hundreds of contracts and agreements. Stephanie is seasoned in discussing investment opportunities with potential scientific and financial partners. In addition to being an author on a number of scientific papers, Stephanie trained at the Center for Emerging Technology in the Bio-Entrepreneur Development Program.
Sriram Devanathan, Ph.D.
Principal
Sriram Devanathan, Ph.D, leads research activities at MGS by overseeing and coordinating with other partners. He has a strong molecular and biomarker discovery expertise. He has served as Life Science consultant conducting multiple technology and market evaluations, Due Diligence, and Business plan evaluations and is a graduate of Square One program from Centre for Emerging Technologies. With this unique skill set, he leads MGS activities to demonstrate preclinical proof of concept and clinical trial of cancer theragnostic agents.
Our Board
Dennis Hallahan, MD
Stephanie Hallahan, MBA
Michael Kinch, Ph.D.
Michael S. Kinch, PhD, is the associate vice chancellor and director of the Center for Research Innovation in Business at Washington University in Saint Louis. Michael’s scientific expertise includes pre-clinical drug development for cancer, immunological and infectious diseases with small molecules, monoclonal antibodies and other biologics. Michael was a professor at Purdue University, studying monoclonal antibody targeting of cancer and went on to lead oncology at MedImmune Inc., and was Chief Scientific Officer at Functional Genetics Inc and Managing Director of the Yale Center for Molecular Discovery.